Visualizing the Brain Thinking
Exploring the Brain Mysteries
Cellular and Sub-cellular Resolution
Free-behaving Animal Stable &
at Different Focal Planes
FIRM-TPM is a miniaturized microscope without sacrificing imaging resolution, speed, fluorescence signal and imaging stability. It is the first microscope being able to capture dynamic image from neural or single spines in freely moving mice worldwide. This innovation was awarded "Method of The Year 2018" with other free-moving animals imaging methods by Nature Methods, and it won such a title”a revolutionary new tool for neuroscience research."Learn more>
The fast high-resolution miniature two-photon microscope (FIRM-TPM) acquires the first batch of cellular-resolution imaging data of single neurons and spines in freely behaving mice all over the world.
This head-mounted microscope can capture calcium dynamics of neurons and spines in awake mouse, effectively transmit 920-nm femtosecond laser pulses to obtain GFP or GCaMP signal, and track the same nueronal population in the same brain region accross multiple days or weeks. Particularly, it can not only be integrated with a Z-scanning module for three-dimensional imaging and multi-plane imaging in the study of neural circuitry, but can also be combined with optogenetics to precisely manipulate neural activity. FIRM-TPM has been widely used in in vivo imaging, especially in the field of neuroscience, and its application has been well extended to the fileds like skin imaging, stem cell study, diagnosis and treatment of diseases, etc.Learn more>
Based on our expertise in the R&D and production of miniature two-photon microscope, we offer advanced optoelectrinic product series, which includes 1030 femtosecond fiber laser, 1560 femtosencond fiber laser, ect.
We offer a product line of miniature microscope relevant parts for in vivo imaging that uses the wearable microscope.
Address：Room 508, 5th Floor, Building 1, No. 13, Cuihu Nanhuan Road, Haidian District, Beijing, PRC
Tel：+86 10 6254 6960
Address：B2-1，Building 16，Treehouse，73 Tanmi Road, Jiang Bei Xin Qu District, Nanjing, Jiangsu, P. R. CHINA
Tel：+86 25 5889 5768
Tel：+86 400 998 9826
Tel：+86 400 998 9826
Method of the Year 2018
China's Top Ten Scientific Advances in 2017
China's Top Ten Progress of Optics in 2017
China's Top Ten Medical Technology News of the year In 2017